Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2017 Vol: 9 Issue: 9

Anticancer Potential of Operculina Turpethum in MCF-7 Human Breast Cancer Cell Lines

Abstract

Objective: This study aims to evaluate the anticancer potential of Operculina turpethum toward MCF-7 human breast cancer cell lines. Materials and methods: Different concentrations of ethanol extract and choloroform extract of Operculina turpethum roots were investigated for their anticancer potential in vitro through MTT assay in MCF-7 human breast cell lines. Results: The ethanol extract and the chloroform extracts of Operculina turpethum showed dose dependent inhibition of cell growth. Out of the two extracts chloroform extracts showed highest inhibition when compared with ethanolicextracts of Operculina turpethum. Conclusion: the plant Operculina turpethum showed excellent cytotoxicity activity against MCF-7 cells, hence it can be used in the development of newer anticancer drugs.