The present study of antimicrobial activities of various crude solvent extracts of Dodonea viscosa were determined against a wide variety of pathogenic bacteria. Crude extracts of Dodonea viscosa shows mild to significant activities for most of the treated bacteria. Crude extracts of n-hexane, dichloromethane, ethyl acetate and methanol showed antibacterial effect against most of the tested organisms. It has been expected that the present work on antimicrobial screening of the plant materials will help researchers who wish to work in designing clinical drugs concerning the killer diseases.