Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 2

Anti gastric ulcer activity of Ficus nervosa bark in wistar albino rats

Abstract

The effect of chloroform, ethyl acetate and ethanolic extract of ficus nervosa bark was investigated in rats to evaluate the anti-ulcer activity by using aspirin, alcohol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, pH, free acidity, total acidity and ulcer index. The results indicate that the ethanolic extract 200mg/kg significantly decreases the volume of gastric acid secretion, pH, free acidity, total acidity and ulcer index with respect to standard.