Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 10

Anthelmintic activity of Hibiscus rosa sinensis (Malvaceae) leaves

Abstract

Hibiscus rosa sinensis belonging to family Malvaceae is a glabrous shrub commonly known as the Chinese hibiscus, China rose and shoe flower. Present study is carried out to investigate and prove ethanomedicinal value of the plant. Authenticated leaves were taken for the study includes extraction of leaves using different solvents and evaluation of Anthelmintic activity. Coarse dried leaves of the plant were extracted successively by soxhlet using petroleum ether, ethanol, methanol, ethyl acetate and distilled water as a solvent according to their increasing polarity. Extract were tested for Anthelmintic activity using Pheretima posthuma as a species of earth worm and compare the paralysis time and death time with standard drug Albendazole. Ethanolic and Aqueous extract shows comparable Anthelmintic activity with standard drug Albendazole. Ethanolic and aqueous extract were tested by different chemical tests. It showed the presence of tannins, flavonoids compounds. These phytoconstituents may responsible for the said activity