Chlorella vulgaris is widely cultivated micro algae found in water bodies as it is rich in nutrients and its component of phytoplankton. C.vulgaris is useful in biomass production in commercial level as it contains proteins and minerals. In this study the value added biochemical compounds in C.vulgaris were analyzed from different cultures. The amount of total carotenoids, protein, vitamin, pigments and phenolic compounds were examined. C.vulgaris extracts possessed great potential antibacterial activities against four bacterial strains with inhibition zones ranged 8-15mm and MICs values ranges from 25-40É¥g/mL.Thus, it could be suggested that the C.vulgaris is useful biosystem for production of biochemical compounds possess an antimicrobial principles.