Objective To study the actual clinical efficacy of nimodipine treatment of cerebral hemorrhage after cerebral hemorrhage.. Method take the 60 patients with ischemic brain injury after cerebral hemorrhage in the hospital from April 2012 to April 2014 as research subjects who were randomly divided into experimental and control group.Each group had30 people. The control group took conventional treatment model, and while the experimental group took intravenous infusion of 10mg nimodipine based on the treatment model of the control group each day . After the treatment period, compare the treatment of the two groups and take statistical analysis for data processing. Results As for the clinical treatment efficacy, the efficacy of nimodipine treatment of ischemic brain injury after cerebral hemorrhage in the experimental group was significantly better than the control group. And two groups had significant differences (P <0.05). Conclusion In the clinical treatment of patients with ischemic brain injury after cerebral hemorrhage, the use of nimodipine as therapeutic drug has a more significant advantage, it is worth actively promoted in clinical practice.