Original Articles: 2016 Vol: 8 Issue: 7
An efficient synthesis of biologically active 7-aryl-11,12-dihydrobenzo[H]pyrimido-[4,5-b]quinoline-8,10 (7H,9H)-diones
Abstract
Organocatalyst has been used as a green catalyst for the synthesis of 7-aryl-11,12-dihydrobenzo[h]pyrimido-[4,5- b]quinoline-8,10(7H,9H)-diones via a one-pot three component condensation reaction of aromatic aldehydes, 1- naphthyl amine and barbuturic acid in solvent water. The environmentally benign, mild reaction conditions and excellent yields of desired products are some of the agreeable features of the method.