Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 3

Amperometric and differential pulse voltammetric determination of 5-Hydroxy-L-tryptophan in pharmaceutical samples using gold modified pencil graphite electrode

Abstract

Quantitative evaluation of 5-Hydroxy-L-tryptophan (5-HTP) in seed powder of Griffonia simplicifolia (pharmaceutical tablet source) using gold modified pencil graphite electrode (GPGE) was carried out by differential pulse voltammetric technique (DPV) and amperometry. The percentage of 5-HTP detected by DPV and amperometry is concurrent with that of Uv-Vis spectroscopic results. GPGE shows high electro-catalytic activity and excellent analytical performance towards the oxidation of 5-HTP.