The study of biological indicator organism is more important than analyzing water or sediments for monitoring heavy metal pollution in the aquatic environment .Non-essential elements enter the animals and accumulate to the different organs so that chelating agents are most versatile and effective antidotes for eliminate the metals toxicities. The aim of our present study is to find out bioaccumulations of aluminium and the effects of chelating agents DFO and DFP in brain and liver tissues of Cirrhinus mrigala by using Inductively Coupled Atomic Emission Spectrometer (ICP-AES). This study finds out the accumulation of aluminium is Brain> Liver. The present result suggests that DFO and DFP reduce the aluminium concentration in the tissues of Cirrhinus mrigala fingerlings and both are efficient chelators. Aluminium toxicity is a wide spread problem in all forms of life, including humans, animals, fishes, plants, and cause wide spread degradation of the environment and health.