In this paper, the treatment efficacy for gastrointestinal tumor patients with hypercoagulable states by Ginkgo injection was researched. The levels of Fib, D-Dimer, PLT of gastrointestinal tumor group with 98 patients and health group was observed and analyzed by statistics methods, and 98 patients was divided into two groups by random, one is treated by Ginkgo injection as treatment group, the other is treated by low-molecular-weight heparin sodium injection as control group, and treatment effect between the two groups was observed. In the experiment, the levels of Fib, D-Dimer, PLT in gastrointestinal tumor patient group were significantly higher than health group (P<0.05), and they were both lower than before after the treatment in treatment group and control group. There were 3 patients had untoward effect in treatment group, and there were 21 in control group. The occurrence of skin ecchymosis and melena in treatment group was lower than control group (P<0.05). The experimental result shows that the Ginkgo injection is an effective and safe therapy to cure hypercoagulable states.