Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 4

A study on the synthesis and bactericidal efficacy of certain poly(ester-amides) containing 2,5-bis(benzylidene)cyclopentanone moiety in the main chain

Abstract

A series of four poly(ester-amides) were synthesized by direct polycondensation of an aromatic diacid namely 4,4´-oxybis(benzoicacid) and 4,4´-biphenyldicarboxylic acid with a diamine namely ethylene diamine and a diol namely 2,5-bis(4-hydroxybenzylidene)cyclopentanone (BHCP) and 2,5-bis(4-hydroxy-3-methoxybenzylidene) cyclopentanone (BVCP) in pyridine using diphenyl chlorophosphate as the condensation agent. These poly(esteramides) were characterized by qualitative solubility data and viscosity values. The microstructure of the repeating units existing in the poly(ester-amide) backbone was established by FT-IR, 1H NMR and 13C NMR spectroscopic techniques. The inhibitory activity of the bisbenzylidenecyclopentanone diols and their poly(ester-amides) against pathogenic bacteria is well documented.