Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 6

A study on phytochemical analysis and antimicrobial activity of Hyptis suaveolens (L.) poit

Abstract

In the present work an attempt has been made to carryout screening phyto constituents and antimicrobial ability of various extract of Hyptis suaveolens (L.) poit .The aim of the study is to select an active plant extract useful in developing new lead compounds to control infectious disease. Antimicrobial activity was screened by disc diffusion method. Antibacterial and antifungal activities of aqueous, ethanol, methanol, chloroform extract of Hyptis suaveolens (L.) poit were tested against Escherichia coli, Staphylococcus aureus, pseudomonas aeruginosa, proteus vulgaris and Aspergillus Niger, Aspergillus flavus, Fusarium, Rhizopus. The antimicrobiall activity was observed by measuring the width of the inhibitory zones. The extent of antimicrobial activity is varied depending upon solvent that has been used. Chloroform extract showed good inhibitory activity against Escherichia coli, Staphylococcus aureus. Ethanolic extract showed highest inhibitory activity against pseudomonas aeruginosa, proteus vulgaris. For Aspergillus Niger , Methanolic extract showed maximum inhibitory activity where as chloroform extract showed maximum inhibitory zone against Aspergillus flavus. Methanolic extract showed best inhibitory ability against Fusarium where as chloroform extract showed highest inhibitory action against Rhizopus. Finally it can be concluded that the active chemical compounds present in Hyptis suaveolens (L.) poit showed certainly fine place in treatment of bacterial and fungal infectious disease.