Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 6

A simple spectrophotometric assay of Montelukast in Pharmaceutical formulations


A simple and sensitive spectrophotometric method for the estimation of montelukast is developed by the formation of ion pair complexe with wool fast blue. The ion pair complex is formed by the interaction of drug with wool fast blue. Wool fast blue is insoluble in water and soluble in chloroform. The organic layer is extracted from chloroform and the absorbance of organic layer is measured at 585 nm against chloroform blank.