In the most ancient Indian traditional system of medicine (Ayurveda) diuretics are called as Muttra- virechanya dravya. These agents were widely explored in Indian ancient system of medicine. Diuretics cause increase in the rate of urine flow rate thus employed in numerous disorders like hypertension, anxiety, cardiovascular disorders, diabetes mellitus and liver degeneration diseases. The aim of this review is to highlight the work on diuretics of plant origin. The selection of papers was made using the most relevant databases for the biomedical sciences on the basis of their traditional use. The numerous diuretic plants with their active phytoconstituents have been explored. The present paper also involves various plant drugs and their pharmacological profile which focus on the dose administered, bioactive extract involved in diuretic mechanism. This work may prove a milestone in selection of medicinal plant for carrying their work on the diuretics.