Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 5

A new method for the synthesis of juglone


In the present study, an appropriate synthetic route was adopted to produce the target synthesis of Juglone. In the first of these objectives, 5-nitro-1,4-naphthoquinone had been synthesized by direct nitration of 1,4-naphthoquinone in the presence of water and sulfuric acid. Then the intermediate synthesis of 5-amino-1,4-naphthoquinone was obtained by the reduction of nitro. Finally, Juglone was produced after the hydrolysis of diazonium salt of 5-amino-1,4-naphthoquinone. The chemical structure of the product obtained by the process of the present study was verified by IR and 1H NMR. The data accord well with those recorded on literatures.