A new flavone, 7,8,2¢ ,3¢-tetramethoxyflavone (1) together with three known flavones, 5,7,2¢ ,3¢ -tetramethoxyflavone (2), skullcapflavone I 2¢-methyl ether (3) and echioidin (4), and two known labdane type diterpenoids 14-deoxy- 11,12- didehydroandrographolide (5) and neoandrographolide (6) were isolated from the whole plant of Andrographis beddomei. The structural elucidation of the new compound (1) and the known compounds (2-6) have been established by extensive 1D and 2D NMR spectral studies.