Current study was carried out to compare the effects of eight weeks aerobic exercises, using lipoherb capsules, and a combination of both on the levels of ALT, AST, ALP and GGT in men with nonalcoholic fatty liver. Forty men with nonalcoholic fatty liver, average age of 37±8 and average weight of 94 ±6 were divided randomly into four groups with 10 members in each group: control, exercise, lipoherb, and exercise+lipoherb. Exercise group did walking and running on treadmill, pedaling on a bicycle ergometer and L-optical with 55% maximum heart beating in first week and 40 % in last week. Lipoherb group used three capsules daily before each meal, and combination group used capsules plus exercises. ALT, AST, ALP, and GGT levels in blood were measured before and eight weeks after treatments. Obtained data were analyzed using one way analysis of variance and means were compared using Tukey test at 5 % probability level. ALT and AST levels of serum were reduced significantly in all three experimental groups whereas ALP and GGT amounts were not affected. The highest reduction was related to combination group. Overall, patients with nonalcoholic fatty liver are recommended to do aerobic exercises plus using lipoherb capsules to reduce ALT, AST, ALP, and GGT enzymes.