Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 6

A comparative study of two different doses of fentanyl with 0.125%bupivacaine through caudal route for pediatric anesthesia and analgesia


Regional anesthetic techniques have become more popular in the recent years with the primary advantage being lowering of general anesthetic requirement and provision of good postoperative pain relief. Single shot caudal epidural anesthesia is the most commonly performed regional technique in pediatric anesthesia. The objective of this study is to compare the efficacy of postoperative analgesia, comparison of pain scores and duration of analgesia between two different doses of inj.fentanyl along with bupivacaine through caudal route for pediatric patients undergoing elective infraumbilical surgery. Our study was done in 50children randomly divided into two groups of 25 each. Group I received 1ml/kg of 0.125%bupivacaine plus fentanyl 0.5μg/kg and group II received 1ml/kg of 0.125%bupivacaine plus fentanyl1μg/kg for caudal block post induction. Postoperatively patients were assessed for efficacy of analgesia with comparison of pain scores (MOPS) and duration of analgesia with requirement of rescue analgesic for duration of 24hours.MOPS was 0-2 in 40 %( Group I) compared to 93.3 %( Group II). Difference in the duration of analgesia was statistically significant with mean duration of 390±50.28min in Group I compared to 440±48.73min in Group II. Requirement of rescue analgesic was also more in Group I (96%).compared to Group II (72%). We hereby conclude that 1μg/kg of fentanyl with bupivacaine 0.125% provides postoperative analgesia for longer duration with less requirement of rescue analgesics as compared to 0.5μg/kg of fentanyl with bupivacaine0.125%without any major postoperative complications.

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