+44 1625708989Synthesis, reactions and biological evaluation of pentadecanyl benzoxazinone and pentadecanyl quinazolinone derivatives
Author(s): Abdallah A. El-Sawy, Shaaban K. Mohamed*, Abd El-Monem M. F. Eissa, Ahmed H. Tantawy and Yvette A. IssacNew series of fatty chain derivatives ofbenzoxazinones and quinazolinones have been synthesized from the two simple precursors of palmitoyl acid chloride and anthranilic acid. Antibacterial and anti-fungal inhibition effect of all products has been investigated. Compounds1, 3, 8, 12 and 15 showed high inhibitory effect towards gram negative and gram positive bacteria while compounds3, 6 and 7 exhibitedhigher anti-fungal effect. The structure of all products has been characterised by IR, NMR, Mass spectra and elemental analyses.
PDF