Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

Synthesis, characterization and antimicrobial activities of 2,2�¢���²-dinitrodiphenylmethanes

Author(s): A. Jepa Malar*a, M. Christudhasa and G. Allen Gnana Rajb

The present study reports the synthesis of 2,2′- dinitrodiphenylmethanes from 2-bromoaniline and formaldehyde in acidic medium followed by nitration using potassium nitrate in 98% H2SO4. Dichloro derivatives of 2,2′- dinitrodiphenylmethanes have been synthesized by Sandmeyer’s reaction. The chemical structure of these compounds have been confirmed by UV-visible, FTIR and 1H-NMR spectroscopic analysis. The compounds have been screened for their antibacterial and antifungal activity.

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