Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

Synthesis and pharmacological evaluation of some substituted imidazoles

Author(s): D. D. Bhragual*1 , N. Kumar1 and S. Drabu2

Titled compounds N-1-phenyl 3- substituted phenyl indolo (2, 3) imidazole was prepared by condensing different aryl aldehydes with N-1-phenyl isatin in presence of ammonium acetate and glacial acetic acid. N-1-phenyl isatin was prepared by reaction of isatin with chloro benzene in presence of tetrahydrofuran and triethyl amine. Synthesized compounds were checked for there anticonvulsant activity.

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