Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Synthesis and antimicrobial activity of 3-(substituted phenyl)-1-(7-substituted coumarin-3-yl)prop-2-ene-1-ones

Author(s): Abida, Saleh Alaqel, Mohd. Imran, Said A. El-Feky and S.A. Khan

A series of 3-(substitutedphenyl)-1-(7-substitutedcoumarin-3-yl)prop-2-ene-1-ones was synthesized by the condensation of 5-substituted-3-acetylcoumarins with four chlorosubstituted aromatic aldehydes. The structures of these compounds were elucidated on the basis of IR and, 1H-NMR. These compounds were further evaluated for their antimicrobial activity.

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