+44 1625708989Optimizational Studies of Salbutamol Sulphate Mucoadhesive Buccal Patches
Author(s): Jane CarrollDesigning and evaluating mucoadhesive buccal patches of Salbutamol Sulphate is a complex process. The study is
produce an effective, safe and reliable delivery method for this asthma medication, enabling it to be administered
through the buccal cavity and absorbed directly into the bloodstream. The first stage of design is to determine the
appropriate formulation for the patch. The drug, Salbutamol Sulphate, needs to be combined with a bioadhesive
polymer such as Hydroxypropyl Methyl Cellulose (HPMC). This will help it adhere to the mucosal surfaces and
increase its retention time, allowing the drug to be released gradually over an extended period. The proportion of
drug and bioadhesive material must be carefully optimized to ensure sufficient dosage delivery, yet not compromise
the patch's adhesion properties.
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