Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

A Novel Synthesis of 2,5-Dibromo-3-[2-2(Methoxyethoxy)Ethoxy]Methylthiophene

Author(s): Yu-Quan Zhang, Yan-Chun Li, Ji-Hua Zhu and Guo-Zhe Guo

A new synthesis of 2, 5-dibromo-3-[2-(2-methoxyethoxy) ethoxy]methylthiophene, which was prepared in good to high yield in three steps from glycol monomethyl ether glycol as starting material under mild conditions,is reported. Synthesis of intermediates 3-[2-(2-methoxyethoxy)- ethoxy]methylthiophene is reported for the first time.

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