A facile and efficient ultrasound-assisted chlorosulfonic acid catalyzed onepot synthesis of benzopyranopyrimidines under solvent-free conditions

Abdulkarim M. A. Al-Kadasi; G. M. Nazeruddin

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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A facile and efficient ultrasound-assisted chlorosulfonic acid catalyzed onepot synthesis of benzopyranopyrimidines under solvent-free conditions

Author(s): Abdulkarim M. A. Al-Kadasi, G. M. Nazeruddin

A facile and efficient ultrasound assisted Chlorosulfonic acid catalyzed one pot synthesis of benzopyranopyrimidines under solvent free condition via three-component condensation of 4-Hydroxy-coumarin with various substituted benzaldehydes and urea/thiourea was developed. This method gives the desired product in excellent yields in short reaction time with ease of work up.

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